Thermo Fisher Scientific has released a food and environmental safety testing system based on the TSQ Quantum Access Max triple-stage quadruple mass spectrometry system and Tracefinder software.
The system can perform structural confirmation.
Library matching lets it confirm and quantitate hundreds of compounds in a single experiment, increasing sample throughput and lowering cost per sample.
Dipankar Ghosh, marketing manager for environmental and food safety solutions at Thermo Fisher, said: 'The built-in methods database reduces method development time from hours to minutes by providing optimised conditions for analytes.' The TSQ Quantum Access Max mass spectrometer (MS) is based on the TSQ Quantum triple-stage quadruple platform and features a mass range of m/z 10 to 3,000.
The system can perform up to 3,000 highly selective reaction monitoring (H-SRM) acquisitions, enabling a higher tolerance for precursor ion selection for quantitative assays.
This provides increased analyte selectivity, resulting in lower limits of detection and improved precision and accuracy.
Thermo Fisher's high-precision hyperbolic quadruples can perform H-SRM without any significant loss in transmission.
The selectivity provided by H-SRM, followed by quantitation-enhanced data-dependent MS/MS (QED-MS/MS), provides uncompromised quantitative performance at low levels, as well as unequivocal structural confirmation.
The TSQ Quantum Access Max's heated electrospray ionisation probe, the HESI-II, lets it deliver twice the sensitivity of its predecessor.
The instrument's high-speed positive/negative switching at better than 25ms enables multi-residue screening in a single analytical run.
Tracefinder's menu of pre-configured methods and report formats makes screening for routine contaminants a simple process, even for novice users.
The software's simple point-and-click interface prompts the user through the steps to create methods for targeted screening and quantitation: the user chooses the test, builds the sample list, chooses the report options and submits the samples for analysis.
Users access the built-in selective reaction monitoring (SRM) library and choose the liquid chromatography/mass spectrometry conditions to create the desired method.
The sample is then analysed and a report is created based on the selected report template.
Tracefinder also offers improved data security with a rights-based user log-in system that limits access to methods and data.
This ensures that data is not compromised and that changes are clearly recorded.
Tracefinder supports English and Chinese languages and will soon support Japanese.
