Thermo Fisher Scientific has released the Thermo Scientific TSQ Vantage LC-MS/MS, which is up to 10-times more sensitive than the TSQ Quantum, Thermo Fisher's previous triple quadruple instrument.
The TSQ Vantage features unmatched signal-to-noise performance, providing better reproducibility and precision in the quantitative analysis of small molecules, biomolecules and peptides.
The TSQ Vantage offers up to 10-times the signal-to-noise ratio when compared with the Thermo Scientific TSQ Quantum series.
Jonathan McNally, vertical marketing manager of bioanalytical instruments for Thermo Fisher Scientific, said: 'This new system enables scientists working with small molecules, biomolecules or peptides to detect compounds at ultralow quantitation levels and to do so reproducibly with great precision; doing anything less risks data integrity and potentially an entire drug study.' The new S-Lens ion optics system in the TSQ Vantage employs novel electrostatic field technology to capture most ions and efficiently transfer them into the Thermo Fisher Hyperquad quadruple mass analyser.
The S-Lens design eliminates mass discrimination and lowers the gas load on the expensive turbo-molecular pumps.
This keeps the ion optical path cleaner for a longer period of time while maintaining sensitivity.
To maximise the workflow capabilities of the advanced LC-MS/MS technologies, the company is releasing Thermo Scientific Transcend, a sample extraction system for the analysis of complex matrices on the mass spectrometer.
The Transcend system doubles sample analysis while reducing sample preparation time and increasing detection limits.
Transcend leverages instrument sensitivity, auto-sampling and LC columns to deliver the highest productivity platform on the market.
This advanced online sample-extraction system, coupled with highly sensitive MS/MS on the TSQ Vantage, provides an end-to-end workflow solution for analysing drugs and other organic molecules.