Thermo Fisher Scientific has announced the launch of two products designed to increase the productivity of quantitative proteomics research.
Intelligent Selected Reaction Monitoring (ISRM) and Pinpoint software were unveiled at the American Society of Mass Spectrometry (ASMS) 2009 annual conference.
ISRM improves the throughput of SRM assays and Pinpoint software is for automated method development and quantitative analysis of ARM-based targeted peptide assays.
One of the biggest challenges in proteomics quantitation is to simultaneously verify and quantify low-level biomarkers.
ISRM, which is available on all Thermo Scientific TSQ (triple-stage quadrupole) instruments, increases the sensitivity and selectivity of targeted quantitation assays for simultaneously verifying and quantifying targeted proteins.
ISRM is designed to target as many as 1,000 peptides and handle more than 10,000 SRM transitions in a single experiment.
This means it has the potential to decrease labour and cost-per-analysis by increasing the number of peptides targeted in a single analysis.
As part of this integrated targeted quantitation workflow, Thermo Fisher Scientific is also introducing Pinpoint software.
Pinpoint, available as a free download, is designed to simplify the transition from early-stage biomarker discovery to larger-scale, quantitative verification of putative biomarkers and general quantitative proteomics.
