Instrument Business Outlook has selected the LTQ Velos ion trap LC-MS system as its 'Product of the Show' from the American Society of Mass Spectometry (ASMS) 2009 meeting.
The LTQ Velos features a dual-pressure trap and advanced ion optics, making it a fast and sensitive ion trap mass spectrometer.
The dual-pressure trap technology includes two discrete pressure regions that allow the decoupling of ion manipulation and detection.
This enables the use of optimal pressures during analysis, increasing scan speed and resolution.
The outstanding data quality and sensitivity of the LTQ Velos make it ideal for analysing complex mixtures such as the identification of low-level proteins and structural elucidation of metabolites in biological matrices.
For proteomics applications, the LTQ Velos offers improvements in speed and sensitivity, providing greater coverage in the analysis of complex peptide mixtures and increasing the confidence of protein identification at low sample levels.
The multiple fragmentation techniques available on the LTQ Velos enable more confident sequence assignment and post-translational modification (PTM) identification.
Faster scan rates also reduce cycle times by up to 50 per cent, doubling the number of proteins and peptides identified.
For metabolism applications, the dual-pressure trap technology increases fragmentation efficiencies, resulting in faster and more confident structural elucidation.
The improved speed and sensitivity combines with MSn capabilities, maximising throughput while maintaining the superior data-quality required for the identification and quantitation of multiple co-eluting compounds.
