Biotek and Global Cell Solutions (GCS) have announced they will collaborate at Labautomation 2010.
Biotek has produced a poster titled 'Automation of a Microplate Cell-Based Assay to Measure Activity of the Histamine H1 G Protein-Coupled Receptor Using a Novel 3-D Cell Culture Technique'.
It is the first in a series of collaborative publications detailing the use of Biotek's microplate instrumentation for various cell-based assays.
The poster details the use of Biotek's Microflo Select Dispenser, Precision Automated Microplate Pipetting System and Synergy 4 Multi-Mode Microplate Reader with a novel 3-D cell culture method and FRET-based assay to measure activity of a histamine H1 G protein-coupled receptor.
Biotek used the Biolevitator and GEM technologies to provide transformed cell types.
At Labautomation 2010, Biotek will display its Microflo Select and Precision along with the successor to Synergy 4 and latest microplate technology - the Synergy H4 Hybrid Microplate Reader.
The new Synergy H4 combines high-performance filter-based detection and flexible monochromator-based detection in one compact instrument.
This unique hybrid of both technologies provides for endless flexibility in current and future microplate-based assay choice.
This collaboration is an opportunity to explore new paradigms for cell-based assay workflows and microplate-based screening of 3-D cell cultures.
Peter Banks, scientific director at Biotek Instruments, said: 'We are particularly interested in collaborating with companies that provide novel enabling technologies such as the Biolevitator and GEM technologies for improving cell-based assay workflows.
'Being able to dispense cells directly into the assay without enzymatic detachment offers a unique workflow advantage and potential benefits to cell health and assay performance,' he added.
Future studies will include primary cell lines as well as kinase screening, ADME/Tox and live cell assays.
The Biolevitator is a compact culture device that reduces operating costs while improving consistency and simplifying handling.
The Biolevitator utilises the GEM technology, a magnetic culture particle that enables users to pipette transformed, primary and stem cells directly from culture to assay without enzymatic detachment and replating.
