Lab901 will present its Protein Screentape platform, which can deliver the practical at-line monitoring of monoclonal antibody production, at Bioprocess International.
According to the company, the at-line monitoring of antibody production by SDS Page has traditionally been impractical owing to the high cost per test point and long analysis time.
With its rapid staining protocol and automated sample handling, electrophoresis and data presentation, the Protein Screentape platform can deliver information on yield, purity and molecular weight within a few minutes.
Samples can be analysed directly from the bioreactor with no need to purify or filter the media.
The analysis of media containing high levels of serum is also possible using Protein Screentape.
Lab901 application scientist Adam Inche said: 'It is now possible to assess antibody production by SDS Page on a day-by-day or even hour-by-hour basis, making this information invaluable not only for process optimisation but also for batch monitoring.
'Using this data, our clients will be able to make more informed decisions on when to harvest their bioreaction batch, thereby saving them time and money,' he added.
