Symyx Technologies has released the Symyx Direct 7.0 data cartridge for registering, searching and retrieving chemical and biological entities stored in relational databases.
Symyx Direct 7.0 is said to improve research-and-development efficiency, project team collaboration and IP management by enabling multidisciplinary project teams to visualise, explore and compare novel macromolecular sequences and chemical structures stored in a single, fully searchable corporate registry system.
Many scientists are searching for ways to reduce off-target effects and improve the stability of chemically modified short interfering RNA (siRNA) sequences, peptides and other large molecules.
Aiding these efforts, Symyx Direct 7.0 supports natural post-translational modifications (PTMs) and custom modifications while also providing support for D-amino acids and complex cyclisations, including the imidazolinone fluorophore found in the fluorescent proteins.
Symyx Direct 7.0 offers a new, hybrid representation that combines the best features of bioinformatics and cheminformatics notations, improving multidisciplinary collaborative research by enabling scientists to: register and retrieve molecules, reactions and biomolecular sequences, including peptides, oligonucleotides and oligosaccharides; search for and view chemical modifications in sequences; and develop structure-activity correlations in sequences.