Anaspec has introduced Mant-ATP and Mant-GTP, said to be useful probes for directly detecting nucleotide-protein interactions at Ex/Em=355/448 nm.
Mant-ATP and Mant-GTP are the fluorescent analogues of ATP and GTP where either the ribose 2'-hydroxy or the 3'-hydroxy group is esterified by the fluorescent methylisatoic acid.
The fluorescence quantum yield of Mant fluorophore is 0.2 in water, which increases significantly in non-polar solvents or upon binding to most proteins.
The highly environmentally sensitive fluorescence of Mant makes Mant-ATP and Mant-GTP useful probes for directly detecting nucleotide-protein interactions at Ex/Em=355/448 nm.
With >95 per cent purity, Anaspec's Mant-ATP and Mant-GTP are said to offer cost-effective value without compromising performance.
