BTX ECM 830 square-wave pulse technology was used to study the development of neural stem cells and progenitors in the developing mouse brain, also known as the ventricular zone (VZ), in utero.
In a recent publication by E.
Stancik and others, researchers targeted the mouse VZ through electroporation using the 3mm platinum Tweezertrodes in order to distinguish the cell-cycle kinetics of short neural and radial glial cells, demonstrating that in utero electroporation is can contribute to understanding of how neural stem cells and progenitors form in the cerebral cortex.
The ECM 830 Square Wave generator is suitable for this application due to its wide range of square-wave voltages, pulse lengths and multiple pulsing capability.
Coupled with the BTX-specialty electrodes, it is widely used for a range of in vivo, in utero and in ovo applications.
In addition to the versatility of the ECM 830 for in vivo applications, the system is capable of efficient transfection in standard cuvettes or in a 96-well format.
