Warwick Analytical Service has developed analytical procedures to enable accurate data to be produced for all types of samples, including organic samples with trace levels of fluorine.
From extensive method validation, typical results are within the +/-0.3 per cent absolute limits considered acceptable for micro-chemical analysis.
The method can detect 0.01ppm fluoride - equivalent to 0.02 per cent in a 10mg sample.
Warwick Analytical Service has developed procedures to remove interferences from samples containing boron, calcium or sulphur.
Analysis of fluorine is carried out by combustion of an accurately weighted sample in a silica oxygen flask over an accurately measured volume of water and TISAB buffer solution.
A fluoride-ion-selective electrode is used to directly measure the potential of a range of fluoride solutions.
The potential of the combusted samples is measured under the same conditions.
The concentrations of the sample solutions are calculated from the derived calibration curve.
Sets of work typically include certified reference materials or organic analytical standards.
Results from these standards and the electrode response are monitored to detect trends in the method.
The accurate micro determination of fluorine in organic compounds will be of interest to industries including food and beverages, environmental monitoring, medical, pharmaceutical and polymers.
