BTX's ECM 830 square wave pulse technology has been used to target and study the development of neural stem cells and progenitors in a developing mouse brain in utero.
As noted in a recent publication by Stancik E et al, researchers targeted the mouse ventricular zone (VZ) through electroporation using the 3mm platinum Tweezertrodes to transfect cells in order to distinguish the cell cycle kinetics of the short neural and radial glial cells during the development of the cerebral cortex.
The wide range of square wave voltages, pulse lengths and multiple pulsing capabilities of the ECM 830 square wave generator make it appropriate for this application.
The ECM 830 and the BTX electrodes are widely used for a range of in-vivo, in-utero and in-ovo applications.
The system is additionally capable of transfecting in standard cuvettes or in a 96-well format.
