Micromeritics scientist Myke Scoggins will be presenting at the PDA Pharmaceutical Freeze Drying Conference in Dusseldorf later this month.
The presentation will focus on surface area measurements on intact lyophilised cakes utilising a special lyophilisation vial holder.
Myke will also be available to discuss his findings that measuring intact cakes gives a better representation of the true surface area of these type samples.
To date, surface area measurement of lyophilised samples required sample manipulation that effectively alters the sample prior to analysis, resulting in a higher surface area than that of an intact cake.
BET surface area measurements generated by the gas adsorption analytical technique can be used to determine shrinkage, collapse and optimal cooling/drying rates as indicators for product performance and manufacturing process optimisation.
In addition to regulatory, process, and technology information, highlights will include aspects of development associated with freeze drying, implementation of new monitoring methods, and procedures to assure product quality and stability.
The Parenteral Drug Association (PDA) Pharmaceutical Freeze Drying Conference takes place in Dusseldorf, Germany, from September 24 – 25.