Novel microfluidic droplet-in-droplet system from Dolomite offers monodisperse double emulsions.
Microfluidic firm Dolomite has released its Double Emulsion System (DES) for creating micron sized emulsion droplets that contain still smaller droplets inside.
The DES is designed to enable unrivalled reproducibility and selectivity of droplet size of both outer and inner phases with oil-in-water-in-oil or water-in-oil-in-water droplets, the company claims.
The system is highly beneficial to applications in the food industry, in pharmaceuticals and cosmetics that use double emulsions as delivery vehicles or encapsulation solutions for various active ingredients, or more generally in paints and coatings, Dolomite says.
The key elements of the DES are its Mitos P-Pump, which delivers precise flow to ensure droplet monodispersity, and the glass Double Emulsion Chip which has a hydrophobic capillary and hydrophilic flow focussing droplet junction, enabling the formation of droplets ranging from 80 to 120?m (outer) and 50 to 90?m (inner) in diameter.
Further advantages the system offers can be found in shielding sensitive biological structures from forces exerted by the sheath fluid, preservation of the linkage between an individual microorganism and the substances it secretes allowing for a screening of metabolites and the opportunity to perform in vitro analyses of biomolecules detached from the respective microorganisms.
