Recent US series of workshops focused on how chip-based surface plasmon resonance technology is adding insight into immunology and infectious disease research
Biacore reports the success of a recent US series of workshops that focused on how its chip-based surface plasmon resonance (SPR) technology is adding insight into immunology and infectious disease research.
SPR product specialists provided an overview from peer-reviewed literature on the use of the technology in areas as diverse as HIV research, parasitology, rheumatology, inflammation, immunogenicity studies and clinical trials.
In addition, Biacore users at organisations such as Aventis Pasteur, University of Pittsburgh, NIH-NIAID, and Amgen discussed how Biacore's SPR technology has enhanced their own research efforts.
"I was particularly interested to learn how SPR can effectively replace Elisa and provide far more real time information, including the kinetics, affinity and specificity of a molecular binding event," said an attending industry director.
"The immunological data presented for preclinical studies into immunogenicity were fascinating." The data presented showed how the sensitivity and power of Biacore's SPR technology in providing rapid, reliable and high-quality information on biological interactions can be successfully applied to the evaluation of immunogenic response in patients receiving novel therapeutic agents.
Applied to such studies Biacore's SPR technology can help researchers to assess the clinical potential for new drugs in clinical trials, to prioritise candidate drugs for further clinical development and to optimise drug dosing regimes.
Further workshop presentations included 'In a bind: How do antibodies neutralise SIV?', 'Antigenicity studies using competitive inhibition assays', and 'Characterisation of oligomeric CD4 constructs: Affinity and avidity determinations and potential use in HIV vaccines'.
Copies of all presentations in the workshop series and a clinical research applications folder pack in the areas of immunology and infectious diseases are available from Biacore on request.
