Enables automated hybridisation of microarrays on slides for applications from gene expression profiling, gene regulation and pharmacogenomic studies to target identification and toxicology
Available from Tecan (Europe), the HS 4800 hybridisation station is a fully automated microarray processing system that offers high reproducibility, flexibility and outstanding performance. The HS 4800 hybridisation station enables automated hybridisation of microarrays on slides for applications ranging from gene expression profiling, gene regulation and pharmacogenomic studies up to the identification of new drug targets and toxicology studies.
To serve these diverse areas the compact HS 4800 has been designed to offer researchers improved reproducibility, superior performance and outstanding ease of use.
Through its modular design, it is possible to easily combine one master system with three extension units (12 additional slides per unit) to process up to 48 slides using up to four different protocols in parallel if so desired.
Incubations may be performed in the range 4-85C.
True parallel processing guarantees exact and reproducible incubation times.
The HS 4800 offers pre-heating of reagents to prevent buffer precipitation, efficient liquid agitation, and on-board slide drying to maximise the quality of results.
Highly uniform liquid distribution ensures reproducibility for all washing steps.
Optional barcode identification and a liquid level sensing system additionally improve the reliability of the process.
Slide loading is facilitated by the use of Tecan's unique slide holders that permit four slides to be loaded simultaneously.
These slide holders also enable seamless connectivity with the Tecan LS series of laser scanners.
The system also has been designed to allow future integration into fully automated robotic systems. Easy-to-use software permits simple programming of application protocols and full process control of all slides in the HS 4800 modules.
This allows the user to quickly determine the status of the system, for example active slides, liquids in use, current processing step up to temperature and the remaining time left in the process.
By combining ease-of-use and flexibility with outstanding quality and performance, the HS 4800 is the perfect solution for scientists demanding improved reproducibility and exceptional safety for automated microarray processing.
In combination with Tecan's Freedom Evo series robotic sample processors and LS series laser scanner, the HS 4800 hybridisation station offers researchers a complete solution for oligonucleotide-, cDNA-, protein- and antibody-based arrays and will help to overcome the automation bottleneck and the lack of reproducibility that currently restrict progress in modern functional genomic studies.
