System simplifies membrane selection and process development at the research scale, linking the chromatography and membrane filtration steps to eliminate multiple manual operations
GE Healthcare has announced the availability of AktaCrossflow, said to be the first fully automated small-scale cross flow filtration system designed to simplify membrane selection and process development at the research scale.
AktaCrossflow links the chromatography and membrane filtration steps, eliminates the need to perform multiple manual operations during process development, and therefore increases workflow efficiency, says GE Healthcare.
AktaCrossflow simulates large-scale conditions from cell separation to final concentration/diafiltration with no cell or protein disruptions.
"This solution allows the researcher to gather reproducible results and maintain complete control during process development.
"It addresses the industry need for an automated, reliable small-scale cross flow separations tool that simulates conditions experienced or anticipated at the industrial manufacturing scale," said Pieter Noordeloos, vice president of marketing process development and manufacturing for GE Healthcare.
"GE Healthcare is committed to designing innovative tools for our research customers in the biopharmaceutical industry".
Designed to handle flexible sample volumes from milliliters to liters, AktaCrossflow is a complete system package that includes hardware, software and membrane devices.
The fully integrated Unicorn software platform monitors and captures sensor data and real-time calculated parameter trends for cell concentration, cell harvesting/clarification and protein concentration applications.
This combination of data capture and analysis in one system eliminates the need for extra steps to effectively evaluate and compare gathered results.
