Protocol and buffer specially designed for use with the HTA slides allows the efficient production and analysis of protein microarrays and is compatible with existing HTA platforms
Greiner Bio-One and Scienion AG have launched a new, integrated system for protein microarrays.
This novel development consists of a protocol and buffer system, which is specially designed for use with the HTA Slides from Greiner Bio-One.
The system allows the efficient production and analysis of protein microarrays.
In addition, it is compatible with and enhances the already available HTA platforms, which the cooperation partners have been jointly offering since the beginning of 2004.
The use of microarrays is gaining in importance as a method for the analysis of the human proteome.
Well aware of the huge complexity within the field of protein analysis, the cooperation partners Greiner Bio-One and Scienion have jointly coordinated their new developments to best address the high demands of customers.
Current users of the HTA platforms for DNA analysis are already taking advantage of Greiner Bio-One's high quality HTA slides as well as Scienion's DNA buffer system, suited to the conditions of current laboratory practise.
Now these benefits of the HTA platform can be capitalised by protein users.
The HTA slides are optionally available with a multifunctional or a 3D-aldehyde surface so that, according to specific needs, two different substrates for the binding of proteins, antibodies or peptides can be applied.
The design and the characteristics of these new surfaces are perfectly suited to the protein protocol and buffer system from Scienion: Scienion's protein protocol and buffer system consist of four buffers and a detailed protocol for conducting protein experiments optimally using Greiner's HTA Slides.
The Scispot-protein print buffer allows users to achieve a homogeneous protein bond to the surface of the HTA Slides.
The Sciblock buffer removes unbound proteins after spotting and in addition saturates the HTA surface.
Subsequently, the Scibind buffer creates optimal conditions for a binding reaction.
Finally, unspecific or non-bound sample material can be washed away with the Sciwash-Pro buffer, ensuring a particularly high binding specificity together with a low background for optimal analysis.
The handling of the HTA Slides in combination with the protein buffer set is oriented directly to current laboratory demands thanks to the high specialisation of the manufacturers, they say.
Since the beginning of 2004 the cooperation partners have been offering microarrays in the form of HTA platforms for a cost efficient high throughput arraying, and their design has already proved successful in the diagnostic market.
The BioScience division of Greiner Bio-One has developed as a leading technology partner to academia, research establishments, diagnostic, pharmaceutical and biotechnology industries on a global basis.
The foundation for this evolution was laid by Greiner Labortechnik through the ongoing innovative use of modern polymers for laboratory and scientific applications.
Today, the BioScience division in conjunction with its sister company Greiner Bio-One Preanalytics has over 1100 employees and generates a turnover in excess of euro 180million per year.
With 19 subsidiary companies and an established network of sales and distribution partners, the group has a presence in over 100 countries.
The successful BioScience product range provides highly innovative and novel solutions for research applications such as high-throughput screening for novel therapeutic agents in the pharmaceutical industry as well as protein coated cell culture products and the development of DNA-Chip technologies for diagnostics.
Scienion is a life science company offering complete solutions in the field of parallel bioanalytics.
Customers include pharma and biotech companies as well as academic research institutions.
Founded in December 2000 as a spin-off of the Max-Planck-Institute for Molecular Genetics, the company was originally focused on biochip platform technologies.
With the successful launch of the Sciflexarrayer dispensing system in 2003, the company's focus has been switched to hardware.
The Sciflexarrayer allows the aspiration of ultra low level liquid volumes from different reservoirs and contact-free micro drop delivery in the picolitre range onto a variety of carriers.
Today, Scienion represents a rapidly growing company, well positioned in the field of ultra low level liquid handling systems including applications in genomics, proteomics and high throughput.
