Scienion AG and Matrical Bioscience have launched the SciSwifter, a high-precision dispensing device for 96, 384 and 1536 microplates.
A time and reagent-saving, drop-on-demand dispenser, it can dispense up to 16 substances in parallel into various multi-well plate formats.
Dispensing range is 100pl to 100 microlitres, with dead volumes close to zero.
Each nozzle has online drop control and optical volume determination.
The SciSwifter can operate as a stand-alone device, and includes integrated touch-screen controls, robotics shuttle and external software API for integration into automated robotics platforms, including Automap, recently launched by Matrical Bioscience.
It allows quick and easy change of setup for different assays, and minimises cross- contamination.
The need for intermediate dilution plates is eliminated by the range of volumes dispensed (six orders of magnitude).
Disposable pen technology (SciSwift) allows preparation, storage, sonication and dispensing of precious reagents in one integrated device.
Substances can be stored directly in the Sciswift dispensing pen, which serves as a closed container, eliminating heat seals and ensuring sample integrity.
Usual applications include dispensing of assay reagents, miniaturisation of assays and dispensing of initial screening, as well as of dose/response experiments from an identical container.
RFID tags for each dispensing pen ensure traceability of precious reagents during storage, retrieval and dispensing.
Primary and secondary assays and dose response tests are made from an identical sample/dilution, with CVs of 2 per cent.