Phenomenex has introduced the Lux Amylose-2 chiral column, adding selectivity to its HPLC products for the identification and resolution of enantiomers.
The new column chemistry incorporates an amylose backbone with a 5-chloro-2-methylphenylcarbamate derivative to give chiral chromatographers an additional selectivity option for these difficult separations.
The Lux Amylose-2 columns complement Phenomenex's Lux Cellulose-1 and -2 chiral offerings.
Enantiomers (mirror images that cannot be superimposed on each other) must be screened separately on their pharmacodynamic and pharmacokinetic properties.
Yet chiral molecules are often difficult to separate and identify using traditional chromatography tools.
The identification of chiral molecules is also important in toxicology studies, flavour and fragrance analysis and environmental applications such as pesticide analysis.
Jason Lam, brand manager for Phenomenex, said: 'Amylose backbones have already demonstrated broad enantioselectivity in chiral analysis.
'The structure of Lux Amylose-2, combined with our unique halogenated derivative, resolves a wide range of enantiomers with unique chiral selectivity.' Lux columns are available in 3 and 5um particle sizes, packed for analytical-scale use or AXIA-packed for preparative applications.
