Corning has introduced Spin-X ultrafiltration concentrators to provide researchers with the ability to concentrate or desalt proteins with greater efficiency and recovery.
The concentrators utilise a vertical membrane design to minimise membrane fouling, and execute rapid ultrafiltration, even with particle-laden solutions.
Key features include: a vertical membrane design that enables faster filtrations with minimal membrane blocking; large membrane area for faster filtrations; integrated dead-stop volume that minimises the risk of concentrating to dryness; low-binding materials that allow for high recovery; graduations printed on the device providing convenience and accuracy; no re-spin necessary for easy handling; and a wide range of cut-offs and volume capacities.
Corning's Spin-X ultrafiltration concentrators are available in three sizes: 500ul, 6ml and 20ml.
Corning's low-binding polyethersulfone (PES) membranes are available with five molecular weight cut-offs (MWCO): 5,000, 10,000, 30,000, 50,000 and 100,000.
The Spin-X ultrafiltration concentrators can be used for multiple applications, including the concentration and desalting of proteins, enzymes, monoclonal antibodies and immunoglobulins; removal of labelled amino acids; HPLC sample preparation; deproteinisation of samples; recovery of biomolecules from cell-culture supernatants (lysates); and concentrating viruses from cells.
Corning Life Sciences provides products and services in the areas of polymer science, biochemistry and molecular biology, glass melting and forming, surface modification and characterisation science.