LGC Standards has introduced a new range of genetically modified (GM) certified reference materials (CRM), all of which meet the recommendations from the European Commission.
Recommendation (EC) No787/2004 suggests that results of the content of genetically modified organisms (GMO) in food and feed should be expressed as copy number ratios.
IRMM has released a string of plasmidic DNA materials: ERM-AD413, ERM-AD415, ERM-AD425 and ERM-AD427 intended as calibrants for the determination of GMO copy number ratios for GM varieties authorised in Europe.
The materials have been processed and certified according to ISO Guide 34 by the Institute for Reference Materials and Measurements (IRMM), which is one of the institutes of the European Commission's Joint Research Centre.
In addition to these new plasmidic DNA-certified reference materials, certified values for copy number ratios have been assigned, as well as the existing certified mass fractions to a selection of existing matrix CRMs, to allow laboratories to implement this recommendation.
With the copy number certification (and the matching plasmidic calibrant), LGC Standards and IRMM are supporting analysts wishing to apply the commission recommendation with quality assurance and measurement tools to do so in a controlled manner.