Details the pathways and interactions involved in the progression of Alzheimer's Disease, providing a valuable resource for neurodegenerative and Alzheimer's research
Sigma-RBI has introduced its Alzheimer's Disease Pathways Poster, a comprehensive compilation of the most current information on Alzheimer's disease.
The poster details the pathways and interactions involved in the progression of this disease, from the cleavage of amyloid precursor protein by secretases, to the final stages of neuronal cell death via apoptosis.
It is a valuable resource for neurodegenerative and Alzheimer's research.
Due to the aging population, neurodegenerative diseases have become more common, and finding a treatment or cure has become a focus of many researchers worldwide.
Alzheimer's disease is the most common cause of dementia, with ageing seeming to contribute to its onset.
UN population projections estimate that the number of people older than 80 years will approach 370 million by the year 2050. Currently, it is estimated that 50% of people over age 85 are afflicted with AD, and that more than 100 million people worldwide will be suffering from dementia in 50 years.
These vast numbers of people requiring round-the-clock care and other services will severely strain medical, monetary and human resources.
Over 200 Sigma-Aldrich Alzheimer's products are highlighted in the poster, including kits for beta-Amyloid, beta-Secretase, and Tau detection, antibodies to amyloid, tau, secretases and cytokines, amyloid peptides, and inhibitors. "This poster is an invaluable tool for anyone researching neurodegenerative and Alzheimer's diseases," said Keith Watling, director of cell signaling and neuroscience.
"The detailed illustration is based on the most up-to-date information available."
