Anaspec has introduced zebrafish (Danio rerio) anti-caspase antibodies for the study of vertebrate development and embryology, toxicology and genomics.
In the field of apoptosis, the zebrafish genome has been found to encode a majority of the components that mediate apoptosis in mammals including humans.
Furthermore, apoptosis-regulating genes, such as the Caspases (cysteine aspartic acid proteases), have been cloned from zebrafish.
Anaspec's Z-fish anti-caspase list includes antibodies for Caspase 2, with immunising peptides derived from the N-terminus (NT) or an internal sequence (IN); Caspase 3a, 3b antibodies targeting specifically the p12 or p17 domains; Caspase 8a, with the immunising peptide derived from an internal caspase 8a sequence; Caspase 9 for p10 and p37 domains; and Caspase-a (caspy) and Caspase-b (caspy-2).
These polyclonal antibodies, raised in rabbits, have been verified in Elisa and western blots using zebrafish lysates.
Antibodies are supplied in 150ul sizes and are enough for 15 mini gels.
The list of Z-fish antibodies includes targets used in apoptosis and autophagy, cell-cycle control, cytoskeleton, glucose and energy metabolism, signal transduction, and immunity research.
