A mycoplasma retentive filter for cell culture media has been launched by Parker Domnick Hunter.
The PROPOR MR has been designed to speed up processing of cell culture media, claiming to provide the fastest filtration times available.
Mycoplasma species are common contaminants of cell culture media with the added problem that their small size and deformability gives them the ability to penetrate the 0.2 micron membranes used for sterilising liquids.
For this reason, 0.1 micron filtration has been widely adopted for the filtration of cell culture media.
However, the higher retention can sometimes come at the price of slower flow rates, longer processing times and increased risk of contamination.
The company developed the PROPOR MR in collaboration with customers using their actual cell culture media feed streams.
They claim the result is a highly retentive filter (typically LRV>10 for Acholeplasma laidlawii) with the fastest processing times for qualified mycoplasma retentive filtration.
In addition, an integral prefilter layer maximises filtration capacity for reduced filter system sizes.
