Kits are designed to reveal antigens that have reacted with a user-supplied antibody on human tissue or cell samples
Cambridge BioScience has extended its range of pathology products with the introduction of Picturet-Plus from Zymed Laboratories. Picturet-Plus is a second generation 'one-step' polymer detection system for immunohistochemical staining.
It has been developed through the further optimisation of Zymed's original 'one-step' system, giving enhanced performance.
Picturet-Plus kits are designed to reveal antigens that have reacted with a user-supplied antibody on human tissue or cell samples.
There are two broad spectrum kits that react with mouse, rabbit, rat and guinea pig primary antibodies.
One features DAB chromagen, and the other AEC.
In addition there are mouse antibody specific and rabbit antibody specific kits.
All can be used in frozen tissue, formalin-fixed, paraffin-embedded tissue and cell preparations.
Each Picturet-Plus kit is sufficient for 150 slides.
Picturet-Plus employs a stable amino acid polymer conjugate.
Developed with high levels of HRP, Picturet-Plus kits eliminate the need to amplify signals with a second antibody.
The target polymer itself replaces the secondary antibody and enzyme conjugate steps that are used in two-step procedures.
The technique is cleaner than traditional methods since it uses fewer protein-based reagents and does not contain biotin or streptavidin.
Background activity due to endogenous biotin or Fc receptors in the sample is avoided.
These products are available from Cambridge BioScience in the UK and Ireland only
