Product range includes all six of the major human liver cytochromes, produced from synthetic genes for the synthesis of drug metabolites
Cambridge BioScience has been appointed UK distributor for Biocatalytics, a specialist in the production of human drug metabolites.
The new product range includes all six of the major human liver cytochromes - 1A2, 2C9, 2C19, 2D6, 2E1, 3A4 - as stable biocatalysts.
These have been produced from synthetic genes for the synthesis of drug metabolites.
Biocatalytics has one of the broadest ranges of enzymes in the world for performing a variety of chemical reactions - suitable for synthesis at different stages from conception to scale up. Biocatalytics's human P450 cytochromes contain the identical metabolic cytochrome enzymes found in human liver and are useful for producing significant quantities of drug metabolites that are identical to those formed in the human body.
All the necessary components have been combined in a lyophilised formulation - just add water and the drug to be metabolised.
Using these biocatalysts, human drug metabolites can be produced in a single step in just one day.
Even secondary metabolic products can be produced, identified and isolated.
