First point of reference for any person wishing to screen references to drugs before turning to more detailed primary literature, such as the original patent application or research paper
Pharmaceutical Substances (PS), Thieme's online database for pharmaceutical ingredients, is now offered by Fiz Karlsruhe via STN International.
More than 2300 ingredients are now searchable online, efficient search functions and bi-annual updates allow for quick access to topical information.
PS (produced by Georg Thieme Verlag, Stuttgart, Germany) is designed to be a complete reference guide to every pharmaceutical compound of significance. It provides a compendium of some 2300 active pharmaceutical ingredients (APIs) and approximately 8200 reaction schemes of interest to the chemical and pharmaceutical industries.
PS is said to be an invaluable resource for anybody involved in the design, discovery, development, and evaluation of drugs.
PS covers all substances contained in drugs currently on the market, and thereby provides important basic information for chemists working in the pharmaceutical industry.
PS was initially offered by Thieme as a printed version in one, later two volumes (Pharmaceutical substances - syntheses, patents, applications) and is now also available electronically.
The new database PS on STN contains the same high quality data available in Thieme's electronic version, and is not offered by any other online host.
PS is a first point of reference for any person wishing to screen references to drugs before turning to more detailed primary literature, such as the original patent application or the original research paper.
Extensive indexing provides the user with a fast and easy way to compare pharmaceutical ingredients.
For each active pharmaceutical ingredient, reaction schemes for the most important ways of synthesis are available.
Starting substances, intermediates and active ingredients are structure-searchable.
Reactants and products are structure-searchable with a single reaction query. Included in the database are all compounds approved by the US Food and Drug Administration, as well as commercially successful ingredients or those judged to have great commercial potential. PS is updated twice a year with approx 50 new ingredients. "PS offers a valuable supplementation of STN's comprehensive pharmaceutical information," explains Rainer Stuike-Prill, head of marketing of Fiz Karlsruhe's online service centre.
"Our customers will appreciate this indispensable combination of essential substance information, business data and synthetic routes for important drugs". "We are happy that we could realize this new offer for the scientific community together with Fiz Karlsruhe," explains Guido Herrmann, managing director of Thieme Chemistry.
"The STN platform now offers the possibility of systematically searching for information on individual substances, also in various databases at the same time."
