Assisting typical amide syntheses requiring a DCM/DMF solvent mixture, Actu addresses the problem that many carboxylic acids of interest are not soluble in DCM
Argonaut's Actu coupling reagent allows polymer-supported active esters of PS-HOBt(HL) to be prepared in DMF.
Assisting typical amide syntheses requiring a DCM/DMF solvent mixture, Actu addresses the problem that many carboxylic acids of interest are not soluble in DCM.
In alternative syntheses performed in DMF using PS-Carbodiimide with HOBt as the additive, Actu complements the method by providing the additional advantage that the product amide is usually formed in a low-boiling point solvent thus avoiding having to isolate the product from DMF.
