New products fall into three categories: live cell screening and Adme/Tox, reagent platforms and proprietary consumables, and automation and detection
PerkinElmer is exhibiting 19 new products at the Society for Biomolecular Screening (SBS) 10th annual conference and exhibition in Orlando, Florida, this week (September 2004). "As a leader in the drug discovery marketplace, PerkinElmer is committed to helping our customers solve their most pressing problems.
"During this year's SBS, we are launching a host of products aimed at enhancing our customers' transition to cellular screening, mitigating the Adme/Tox bottleneck, and driving fundamental productivity improvements into the drug discovery and development process," said John Danner, vice president and general manager of PerkinElmer's biopharmaceutical business.
PerkinElmer's new products fall into three categories: live cell screening and Adme/Tox, reagent platforms and proprietary consumables, and automation and detection.
The showcased products include.
Live cell screening and Adme/Tox: CellLux uHTS cellular screening system: featuring patented fibre-optic imaging with integrated liquid handling for high-throughput live cell 'inject and read' applications.
The CellLux is ideal for ion channel screening, an increasingly important drug discovery application.
CellEx Poly-D-lysine coated microplates: proprietary new technology to anchor live cells onto a microplate for robust cellular applications a perfect fit with the new CellLux.
Cellular Workstation: fully integrated and automated workstation for conducting live cell screening, tying together PerkinElmer's detection, liquid handling, and chemistry technologies and creating a walk-away, easy-to-use solution for a variety of cellular applications.
ATP-Lite One-step: a high-throughput live cell assay for evaluating compounds' toxic effects on cells. This easy-to-use, scalable approach allows customers to perform toxicity testing during primary screening, thus enabling the elimination of poor candidate compounds much earlier in the drug discovery process.
Reagent platforms and proprietary consumables. Lance Camp: a sensitive, robust, 1536-well capable Camp assay, based upon PerkinElmer's Lance TRF technology, optimised for a wide range of PerkinElmer detection platforms.
Easy-Lite Kinase: an antibody-free luminescence detection method addressing all kinase targets, saving customers precious time and money spent on sourcing and screening antibodies.
Lance Beta-Secretase: an optimised assay kit enabling customers to screen a key target related to Alzheimer's disease in a robust, high-throughput, cost-effective manner.
New AlphaScreen protocols: highly sensitive, homogeneous uHTS assays for the increasingly important applications of ubiquitin and guanylate cyclase screening. OptiPlate 384-HS: microplate specifically designed to reduce background interference for uHTS imaging assays - a perfect complement to the ViewLux uHTS imager.
Image-Mix cocktail: proprietary, red-shifted liquid scintillation cocktail that enables customers to significantly increase throughput of laborious, slow radiometric assays.
Four New GPCR receptor and ligands: key new offerings include Gastric Inhibitory Polypeptide (GIP) and GPR8, thus continuing PerkinElmer's commitment to enabling novel GPCR target research.
Automation and detection. EnVision Turbo AlphaScreen capability: new technology enhancements double the power of current EnVision AlphaScreen detection, thus increasing throughput and sensitivity, as well as expanding applications.
FlexDrop EX: new precision reagent dispenser for rapid dispensing of solvents, reagents, buffers and cells enables dispensing of one to four reagents in volumes from 200nl to 2.0ml, with dispense accuracy of less than or equal to 5%.
The new EX model includes two stacker cassettes with capacity for up to 50 SBS-standard microplates for automated, walk-away processing.
ViewLux uHTS software enhancements: significantly increases screening flexibility, expands data analysis capability, and improves fluorescence performance.
Elisa Workstation: a fully integrated, walk-away workstation, automating traditionally labour-intensive, multi-step Elisa assays.
The Elisa workstation utilises application-specific protocols integrated with PerkinElmer detectors, washers, and dispensers, thus speeding up the process from sample preparation to results generation.
Along with highlighting its array of products at this year's conference, PerkinElmer will also present its 8th annual PerkinElmer Award for Innovation in HTS. This year's award will be presented to Steven Hofstadler of Ibis Therapeutics for his work in mass spectrometry focusing on characterising microorganisms and noncovalent complexes between RNA and small drug-like molecules.
