Reduce the complexity of the proteome

Tecan has announced the introduction of the ProTeam FFE, an innovative solution that offers academic research departments, biotech and pharmaceutical companies radically improved reproducibility and sensitivity for proteomic research. Addressing key barriers that restrict both the quality and speed of large-scale proteomic research, the ProTeam FFE offers a unique combination of innovative technology, high performance, and outstanding reliability.

As the first part of the ProTeam suite of products, the ProTeam FFE reduces the complexity of the proteome and offers unrivalled access to low-abundant proteins due to its capability for continuous sample application.

The ProTeam FFE is a liquid fractionation device that allows the rapid separation of charged molecules and particles without the use of a conventional solid polyacrylamide matrix.

Advanced patented technology for matrix-free separation enables exceptional protein recovery.

This technology may be used to separate a wide range of charged molecules and particles including, for example, cells, cell organelles, cellular fragments and complex protein mixtures.

The ProTeam FFE system permits extremely fast continuous electrophoretic fractionation yielding up to 96 fractions.

For optimal flexibility across a wide range of applications, experiments can be performed with different electrophoretic modes under both native and denaturing conditions.

Rapid run times enable separation and fractionation within 30 minutes.

For maximum performance, the ProTeam FFE is supplied with proprietary reagents (ProLytes) and validated protocols for isoelectric focusing.

Further protocols for zone electrophoresis and isotachophoresis operation modes are possible.

The ProTeam FFE provides the platform to undertake new applications ranging from cellular pathway analysis and the identification of new disease markers up to the characterisation of new drug targets.