Three new illumination modules for inverted microscope create scope to undertake an even wider range of research-level fluorescence applications
With the launch of three new illumination options, Nikon says the versatility of its TE2000 inverted microscope has been increased yet further.
Tirf2, W-Tirf and PA-GFP attachments create scope to undertake an even wider range of research level fluorescence applications - including the unique surface reflection interface contrast (SRIC) to study the surface condition of a specimen.
Unifying the Tirf and epi-fluorescence systems in a single layer, Tirf2 provides much more flexibility for combination with other equipment such as optical tweezers.
Tirf2 widens the range of application bases for the TE2000 from simple epi-fluorescence to intricate observation of living cells at the molecular level.
Single molecular activity in contact with the surface of the coverglass can easily be captured.
Researchers using W-Tirf can achieve high performance epi-fluorescence using the Tirf illumination technique more affordably than ever.
Utilising mercury, xenon, metal halide or high intensity halogen, illumination costs can be kept to minimum without compromising quality, thanks to the superior quality of Nikon's optics.
Photoactivable GFP (PA-GFP) allows easy observation of molecular movement by photic stimulation of fluorescence proteins.
Not only can elevated fluorescence and improved optical contrast between activated and inactivated forms be achieved, but it is also possible for a researcher to selectively activate individual molecules or groups of molecules and easily track their behaviour.
When combined with the new Nikon DS-1QM quantitative camera and Apochromat VC objectives, specifically corrected in the violet region of the spectrum, the TE2000 becomes a very powerful and complete digital imaging system, says Nikon.
