Prepacked with a chromatography medium resistant to harsh cleaning agents, these columns should improve the process of small-scale monoclonal and polyclonal antibody purification
GE Healthcare has introduced HiTrap MabSelect Sure, which it says improves the process of small-scale monoclonal and polyclonal antibody purification by allowing researchers to clean and reuse prepacked affinity columns.
HiTrap MabSelect Sure are columns pre-packed with the new MabSelect Sure, a chromatography medium that is resistant to harsh cleaning agents, such as 0.5M NaOH.
By combining the robust properties of the MabSelect Sure medium with the convenience and reproducibility of the HiTrap column format, the new columns answer the requirements of all researchers who ordinarily purify using conventional protein A products, says the company.
Available in 1ml and 5ml sizes, the HiTrap MabSelect Sure columns are intended for routine purification of monoclonal antibodies and equally useful for process development that can be scaled-up with MabSelect Sure media.
"Monoclonal antibodies are increasingly important as therapies, especially in cancer management and chronic infectious diseases treatments.
"HiTrap MabSelect Sure offers time savings, purification reproducibility and ease of use.
"The robust cleaning procedures ensure that there is no contamination from sample to sample," said Allan Simpson, vice president of research and analysis, protein separations at GE Healthcare.
"GE Healthcare is committed to designing innovative tools for our research customers in the biopharmaceutical industry".
Additionally, GE Healthcare offers a comprehensive solution to researchers for high throughput monoclonal purification, as these new HiTrap columns are an integral part GE Healthcare's Aktadesign and Aktaxpress platforms, designed to help researchers completely automate the purification process and ensure reproducible results.
