First high-content screening and analysis solution being used by bio-pharmaceutical researchers to identify off-target effects in live cells
IBM and Cellomics have launched a customised information
technology (IT) solution that allows biopharmaceutical scientists
and academic researchers to better understand how potential drug
candidates or targets of interest affect cellular function.
new solution, which allows for high-content screening and
in-silico modeling is already being installed at Epoplus, a
biopharmaceutical company developing a novel
low-dose-erythropoietin therapy likely to have a major affect on
the understanding of degenerative diseases, stem cell behavior
and cell biology.
"We are very pleased to form this
collaboration with IBM and Cellomics," said Ferdinand
Bahlmann, president of Epoplus.
"The expertise and
technology they provide greatly reduce the significant cost
associated with screening and evaluating potential cell
By partnering with Cellomics, IBM is
furthering its work in the field of information-based medicine,
the process of improving existing pharmaceutical and medical
practices with knowledge about the human genome.
contextual data that can be obtained about cellular functions
using HCS generates information necessary for modeling and
simulation that empowers biopharmaceutical organizations to
design more accurate trials, reducing time and cost spent making
"In working with Cellomics to build this joint,
turnkey solution, we're able to help organisations like
Epoplus enhance their cellular research capabilities," said
Mike Svinte, vice president, information-based medicine, IBM.
"By putting this technology together in an out-of-the-box
solution, we are hoping to give many more researchers the ability
to test potential drug compounds against crucial, contextual
information about cell structure, function and interaction".
With the goal of delivering an IT solution that can automate and
manage large volumes of data, IBM and Cellomics have combined
Cellomics patented high content informatics (HCi) software with
proven servers, storage and management software from IBM.
resulting HCi appliance offers a scalable architecture that
includes the Tivoli suite of security compliance products, IBM
eServer, user training sessions and Cellomics Store, an
enterprise-level database that stores and manages images and